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Author: Tatiana Chitic Degree: doctor of biology Speciality:  03.00.13 - Human and animal physiology Year: 2009 Scientific adviser: Aurelia Crivoi doctor habilitat, professor, Moldova State University Institution: Scientific council:

Status The thesis was presented on the 6 March, 2009 Approved by NCAA on the 23 April, 2009 Abstract – 0.55 Mb / in romanian Thesis CZU 616.379-008.64:616.15:591.147 1.19 Mb / in romanian 0 pages

Keywords

Summary

For the first time there have been carried out scientific research of the influence of medicinal plants extracts from blackberry (Ribes nigrum), flax (Linum usitatissimum), corn stigmas (Maydis stigmata) and hawthorn (Crataegus monogira) on endocrine pancreas β-cell function, functional activity of thyroid and sexual hormones, that have given a possibility to reveal stimulating of these glands at the incipient stages of experimental diabetes. There was presented the complex study of interdependency of endocrine pancreas, thyroid and sexual hormones in alloxan induced diabetes.

The paper showed that during experimental diabetes endocrine glands increase their activity, as the adapting reaction to endogen metabolic stress caused by β-cells dysfunction. Experimental groups which without medicinal plants extract administration was determined the decrease of insulin secretor cells function. Besides, there was observed the diminution on sexual hormones concentration in alloxan treated groups that allowed evidencing the interrelation of functional deregulations during diabetes.

Thus, experimental results high lighted that vegetable complex action on hormone synthesis processes.

Medicinal plants extracts manifests biosimulative effects on β-cells from Langerhans isles of endocrine pancreas, both with increase of insulin secretion and decreasing hyperglycemic level in the body.

Oficial Reviewers

• Ştefan Ţurcanu
  doctor habilitat, professor, Agrarian State University of Moldova
• Lora Moşanu
  doctor

 Theses