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CNAA / Theses / 2011 / May /

Percularities of diagnosis, treatment and prognostic of the breast noninvasive carcinoma


Author: Chiaburu Simona
Degree:doctor of medicine
Speciality: 14.00.14 - Oncology and Radiotherapy
Year:2011
Scientific adviser: Vasile Jovmir
doctor habilitat, professor, Public Medical Sanitary Intitution Institute of Oncology
Scientific consultant: Nina Bogdanscaia
doctor habilitat, associate professor (docent), Public Medical Sanitary Intitution Institute of Oncology
Institution: Public Medical Sanitary Intitution Institute of Oncology
Scientific council: DH 52-14.00.14-27.03.08
Public Medical Sanitary Intitution Institute of Oncology

Status

The thesis was presented on the 24 May, 2011
Approved by NCAA on the 8 July, 2011

Abstract

Adobe PDF document – 0.49 Mb / in romanian

Keywords

Noninvasive carcinoma, proliferative fibroadenomatosis, diagnostic imaging, morphological diagnosis, surgery, lumpectomies with limphnode dissection

Summary

Volume thesis contains introduction, 4 chapters, conclusions and practical recommendations. The thesis is exposed on 118 typed pages, contains 29 tables, 45 figures. Bibliography contains 188 sources. The results were published in 24 scientific papers.

Study domain is the diagnosis, treatment and prognosis of Noninvasive carcinoma of the breast. Purpose of the thesis: the study of diagnostic, treatment and prognoses percularities of the breast noninvasive carcinoma.

Objectives of the thesis: assessing the clinical, imagistic exam and morphological data of Noninvasive carcinoma of the breast. The complex analyses of clinical, imagistic exam and morphological data and elaboration of treatment in dependence on the extention of the process.

The scientific novelty and originality of the scientific data received from the first time a clinico – imagistic exam algorithm was developed in the diagnosis of the breast Noninvasive carcinoma, intraoperative treatment algorithm tactics of Noninvasive breast carcinoma and algorithm for treatment of carcinoma after the surgery.

The theoretical significance of the work. Complete the knowledge in clinical, imagistic exam and morphological percularities of Noninvasive breast carcinoma and lead to elaboration of the treatment strategy (surgery, combined, complex), which the improvement of treatment efficacy. The assessing of risk factors in Noninvasive breast carcinoma prognoses of treated patients could serve as check point for secundary prophylaxis.

Practical value of the study: it was established risk factors for Noninvasive breast carcinoma which will contribute to prognoses improvement. It was determined the indication for surgery in case of different forms of breast carcinoma in situ for lumpectomies with limphnode dissection in case of different forms and variants of this oncologic pathology such contravercive ad imprevisible, like Noninvasive breast carcinoma. The practical implementation of algorithms developed in our study will influence the optimization of diagnosis and treatment of patients with Noninvasive breast carcinoma, a factor, which will improve the prognosis.

The study results was established in treatment of patients of Noninvasive breast carcinoma into Mammology Departments of Moldavian Oncology Institute, where it was elaborated the algorithms for diagnoses and treatment of Noninvasive breast carcinoma.