Physico-chemical aspects of the process of microbiological synthesis of iron nanoparticles
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StatusThe thesis was presented on the 8 July, 2016Approved by NCAA on the 6 October, 2016 Abstract – 1.86 Mb / in romanianThesisCZU 544.165.546.72(043.3)
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Keywords
iron nanoparticles, molecular mechanisms, biosorption, Dunaliella salina, biomineralization, lactoferrin, molecular dynamics simulationsSummary
Dissertation consists of an introduction compartment, four chapters containing theoretical concepts and personal contributions of experimental and theoretical results, general conclusions and recommendations, references with 232 titles, 2 appendixes, 114 pages of basic text, 22 tables and 48 figures. The obtained results were published in 12 scientific papers.
The field of study: 144.01. – Physical chemistry.
The goal of the thesis consists in the study physicochemical aspects and mechanism of microbiological synthesis of iron nanoparticles. Objectives: elaboration of a methodology for testing microorganisms for identification of their capability of nanoparticles synthesis, in laboratory conditions; identification of the physicochemical factors that favorize the process of microbiological synthesis of nanoparticles; study of some proteins for identification of the mechanisms of the microbiological synthesis of iron nanoparticles.
Originality and scientific novelty. For the first time were established the mechanisms of the microbiological synthesis of iron nanoparticles. For the first time, the molecular dynamics simulations method was used for the research of the mechanisms of the microbiological synthesis of iron nanoparticles. Scientific problem solved consists of the identification of the ion-molecular mechanisms involved in the microbiological synthesis of iron nanoparticles using the strain of green microalgae Dunaliella salina CNM-AV-02, which will contribute to the optimization of the existing microbiological methods of synthesis.
Theoretical significance. The obtained results contribute to the strengthening the knowledge on the mechanisms involved in the microbiological synthesis of iron-based nanoparticles using microalgae. Moreover, it was proved the possibility of using the molecular dynamics simulation methods for the investigation of physicochemical processes on the molecular level.
Applicative value of the present work. The conducted applicative research allowed to develop a method of evaluation of capability of microorganisms to synthesize nanoparticles and optimization of the existing microbiological methods for the improvement of physicochemical parameters of nanoparticles.
Implementation of scientific results. The method of evaluation of capability of microorganisms to synthesize nanoparticles, in laboratory conditions, was tested in the Laboratory of Phycobiotechnology, The Institute of Microbiology and Biotechnology of ASM.
Oficial Reviewers
- Maria Gonţa
doctor habilitat, professor, Moldova State University - Tatiana Isac
doctor, associate professor (docent)
Council's Members
- Tudor Lupaşcu, president
doctor habilitat, professor, Institute of Chemistry of the ASM - Raisa Nastas, secretary
doctor, associate professor (docent), Institute of Chemistry of the ASM - Ion Tighineanu, member
doctor habilitat, professor, Institute of Mathematics and Computer Science - Valeriu Rudic, member
doctor habilitat, professor, Institute of Microbiology and Biotechnology of the ASM - Igor Povar , member
doctor habilitat, professor - Marina Fonari, member
doctor, associate professor (docent), Institute of Applied Physics of the
Theses
