StatusThe thesis was presented on the 25 December, 2008
Approved by NCAA on the 26 February, 2009
Abstract– 0.39 Mb / in romanian
– 0.44 Mb / in russian
ThesisCZU 616-072.7:616.24-002.5-33:616.24-001(002): 611.2
2.77 Mb /
For examination of functional state of aero-hematic and histohematic barriers was applied the method of single-acting measure of gradients, volumes and speeds of transfer respiratory gases in indicated morpho-functional elements of the respiratory system by the using of oxygen methods Riley-Lilienthal, Rouhton-Forster, arterio-venous method Е. Landis, spirography in an closed respiratory contour, tetrapolary reopulmonography of pulmonary blood current and angiotensiotonography of pressure in artera pulmonary using indices of venous hypoxemia (PvO2), metabolic hyperacidity (BE) and isohidric transport as criteria of severity of hypoxic state of peripheral tissues.
Functional study of aero-hematic and histohematic barriers in 280 patients with pulmonary tuberculosis, chronic obstructive and disseminate pulmonary diseases allowed to search the transfer of oxygen and carbonic gas between atmospheric air and cells tissues, and organs mitochondrion like unitary complete inseparably chain of interdependent processes.
Lung, affected by pathologic processes, put up resistance of different degree to the penetration of atmospheric oxygen in inter- and intracellular space, which increase bring to development of arterial hypoxemia not only in tissues of the affected organ, but to the development of venous hypoxemia at the level of histohematic barrier, and in result – to the hypoxic state of all organism: respiratory and unrespiratory hypoxia.
Causes of hypoxia state in different chronic pulmonary diseases are: