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Primary prophylaxis of drug abuse in the Republic of Moldova

Author: Condratiuc Svetlana
Degree:doctor of medicine
Speciality: 14.00.18 - Psihiatrics and Narcology
Scientific adviser: Mircea Revenco
doctor habilitat, professor, Nicolae Testemitanu State University of Medicine and Pharmacy of the Republic of Moldova
Scientific consultant: Larisa Spinei
doctor habilitat, professor, Nicolae Testemitanu State University of Medicine and Pharmacy of the Republic of Moldova
Scientific council:


The thesis was presented on the 8 April, 2009
Approved by NCAA on the 18 June, 2009


Adobe PDF document0.41 Mb / in romanian


CZU 616.89-008.441.33 - 08(478)

Adobe PDF document 1.49 Mb / in romanian
171 pages


epidemiology, adults, substances psyhoactives, risk factors


Primary prophylaxis of alcohol dependence, of drugs and other SPA represents a strategy oriented to risk factors decreasing of drugs use. We examined 2061 adolescents of 12-17 from 31 secondary schools of Chişunău (1103) and Bălţi municipies (958). We performed a survey made according to international standards of anonymous questioning. The survey included questions which revealed directly of indirectly the risk factors of adolescents’ involvement in using of narcotics (socio-demographic data; data of smoking; data of alcoholic drinks use; data of narcotics usage; of reasons and the age of the „first testing” of PAS, of the information level about the narcotics existence, etc.). The percentage of the boys among the questioned in secondary and high schools from Chişinău and Bălţi was 50,3% (1036) and among girls was 49,7% (1025). According to the number of questionned adolescents who „tested PAS” in Chişinău was 16,0±1,1% (р <0,001), in Bălţi - 14,5±1,1% (р<0,001), and on an average it was - 15,3±0,8% (р<0,001). The adolescents were divided according to certain criteria in a basic (main) group, designated as “those who tested PAS” of 315 persons (15,3%) of the general number questioned (Chişinău–176–16,0%, Bălţi-139-14,5%) and a control group which did not “try PAS” (1746). Differences of gene risk factors have been revealed which contributed to involving of adolescents from Chişinău and Bălţi to use psychoactive substances as well as a comparative analysis of data from both cities.

By using of the discriminantive method of the risk factors in involvement and usage of PAS, common for boys and girls who “tried PAS” and which are particular for each sex separately. A risk factor such as an often being in a alcoholic intoxicating state is on the first place (for boys: RR= 6,5 95% iî: 2,8-10,2; for girls: RR=25,0 95% iî: 21,0-29,0), on the second place is smoking of more than 10 cigarettes per day (boys: RR= 5,6 95% iî: 3,7-7,5; girls: RR=8,7 95% iî: 6,3 – 11,1) and on the third place in boys is smoking of less than 10 cigaretts per day (RR= 5,5 95% iî: 2,0-8,4). On the third place in girls is the factors of „a proposal by unknown people to test narcotics” (RR= 8,5 95% iî: 6,2-10,8).

Among protective risk factors of using drugs we revealed: going in for sports (RR= 0,3 95% iî: 0,1-0,6), good results in studies (RR= 0,4 95% iî: 0,1-0,7), good relations with parents (RR= 0,6 95% iî: 0,2-1,9) and the awareness that narcotics is a serious problem of the young people (RR= 0,7 95% iî: 0,85-0,9). Taking into consideration the high level of spreading of narcotism, we consider reasonable to perform prevention measures starting with the age of 9-11.