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Gastropathy in case of Chronic Obstructive Lung Disease: clinic and diagnostic criteria

Author: Nichita Svetlana
Degree:doctor of medicine
Speciality: 14.00.05 - Internal Diseases (with specification: Pulmonology, Gastroenterology, Hepatology, Nephrology, Functional Diagnostics and Endoscopy)
Scientific adviser: Ion Butorov
doctor habilitat, professor, Nicolae Testemitanu State University of Medicine and Pharmacy of the Republic of Moldova
Institution: Nicolae Testemitanu State University of Medicine and Pharmacy of the Republic of Moldova
Scientific council: DH 50-14.00.05-27.03.08
Nicolae Testemitanu State University of Medicine and Pharmacy of the Republic of Moldova


The thesis was presented on the 23 December, 2009
Approved by NCAA on the 18 March, 2010


Adobe PDF document0.29 Mb / in romanian


Chronic Obstructive Lung Disease, gastropathies, gastroduodenal zone cytokines, cellular immunity, ozonotherapy.


Structure of the thesis: introduction, six chapters, conclusions, bibliography consisting of 233 sources, 115 pages of fundamental text, 38 tables, 19 figures. Results of the research were published in 9 scientific papers.

Area of Research:internal medicine

Goal of Research: Studying of clinical peculiarities of erosive-ulcerous defeats of gastroduodenal zones at COLD for development of new diagnostic criteria and schemes treatment of gastroduodenopathies.

Research Objectives:

Methodology:Research of control cases and control therapeutical research.

Scientific novelty: For the first time in Moldova at patients with COLD it is certain of parameters of cellular immunity, of balance of cytokines, of anti-organ antibodies in development of gastropathies; is studied influence of a degree of respiratory insufficiency on a condition of a mucous membrane of gastroduodenal zones; is given the estimation of efficiency ozonotherapy in complex treatment of acutes erosion and pepticis ulcers at COLD.

Scientific value and clinical applicability: The given research has allowed to make a picture of clinical features of gastropathies at COLD, and to study mechanisms of their development. The combination of ozonotherapy with standard anti-ulcerous treatment considerably raises efficiency of therapy of patients with gastropathies at COLD.

Introduction of results of research: The received results are introduced in a clinical practice in MSPI CH MH RM, included in the curriculum on Faculties of Internal illnesses № 6, № 5 and № 3 SMPU "N.Testemitanu".