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Gastropathy in case of Chronic Obstructive Lung Disease: clinic and diagnostic criteria

Author: Nichita Svetlana
Degree:doctor of medicine
Speciality: 14.00.05 - Internal Diseases (with specification: Pulmonology, Gastroenterology, Hepatology, Nephrology, Functional Diagnostics and Endoscopy)
Scientific adviser: Ion Butorov
doctor habilitat, professor, State University of Medicine and Pharmacy "Nicolae Testemitanu"
Institution: State University of Medicine and Pharmacy "Nicolae Testemitanu"
Scientific council: DH 50-14.00.05-27.03.08
State University of Medicine and Pharmacy "Nicolae Testemitanu"


The thesis was presented on the 23 December, 2009
Approved by NCAA on the 18 March, 2010


Adobe PDF document0.29 Mb / in romanian


Chronic Obstructive Lung Disease, gastropathies, gastroduodenal zone cytokines, cellular immunity, ozonotherapy.


Structure of the thesis: introduction, six chapters, conclusions, bibliography consisting of 233 sources, 115 pages of fundamental text, 38 tables, 19 figures. Results of the research were published in 9 scientific papers.

Area of Research:internal medicine

Goal of Research: Studying of clinical peculiarities of erosive-ulcerous defeats of gastroduodenal zones at COLD for development of new diagnostic criteria and schemes treatment of gastroduodenopathies.

Research Objectives:

Methodology:Research of control cases and control therapeutical research.

Scientific novelty: For the first time in Moldova at patients with COLD it is certain of parameters of cellular immunity, of balance of cytokines, of anti-organ antibodies in development of gastropathies; is studied influence of a degree of respiratory insufficiency on a condition of a mucous membrane of gastroduodenal zones; is given the estimation of efficiency ozonotherapy in complex treatment of acutes erosion and pepticis ulcers at COLD.

Scientific value and clinical applicability: The given research has allowed to make a picture of clinical features of gastropathies at COLD, and to study mechanisms of their development. The combination of ozonotherapy with standard anti-ulcerous treatment considerably raises efficiency of therapy of patients with gastropathies at COLD.

Introduction of results of research: The received results are introduced in a clinical practice in MSPI CH MH RM, included in the curriculum on Faculties of Internal illnesses № 6, № 5 and № 3 SMPU "N.Testemitanu".