StatusThe thesis was presented on the 30 April, 2010
Approved by NCAA on the 3 June, 2010
The structure of the thesis: Introduction, 4 Chapters, Conclusions and Recommendations, Bibliography (155 sources), 6 Annexes, 124 pages of the basic text, 44 pictures, 51 tables. The results are published in 44 articles.
The field and objectives of the study: The goal of the study was to determine the sensitive and specific diagnostic value of echocardiography (ECOCG) for a correct diagnosis and decision of the therapeutic or surgical approach in patients with congenital heart diseases (CHD). The objectives: the definition of the most important echocardiographic parameters for a correct decision of surgical treatment and for a postoperative supervision of the patients, the determination of the sensitivity and specificity of ECOCG in the diagnosis of CHD, the comparative analysis of imagistic methods in the diagnosis of CHD, the elaboration of an algorithm for ECOCG diagnosis and decision of surgical treatment in CHD, the elaboration of a normalized protocol of echocardiographic examination of a patient with CHD.
The scientific novelty and originality: The most important ECOCG parameters for performing of correct diagnosis and decision of surgical treatment in the patients with CHD were determined for two groups of patients according to 2 principal groups of CHD subject to the status of pulmonary circulation (ventricular septal defect and tetralogy of Fallot). The sensitivity and specificity of ECOCG in the diagnosis of CHD was determined both for the principal and concomitant malformation. The topic structure of CHD was studied in the Republic of Moldova. The algorithms for ECOCG diagnosis and decision of surgical treatment in these 2 groups of CHD were elaborated.
The theoretical importance and applicative value of the study: The principal ECOCG parameters for the decision of therapy and the estimation of the efficiency of surgical care were determined for these 2 groups of patients. A normalized protocol for ECOCG examination of a patient with CHD was elaborated. The algorithms for ECOCG diagnosis and decision of surgical treatment in the case of ventricular septal defect, tetralogy of Fallot and pulmonary stenosis were elaborated, thus determining the estimation of haemodynamic disturbances and the choice of cardiac surgery.