StatusThe thesis was presented on the 17 June, 2016
Approved by NCAA on the 6 October, 2016
Abstract– 0.43 Mb / in romanian
2.79 Mb /
Incidence, early diagnosis and management of renal and urinary malformations treatment in children
Doctoral thesis in medicine. Chişinău, 2016. Thesis structure: Introduction, five chapters of
personal study, conclusions and recommendations, bibliographic index – 125 sources. The thesis
is exposed on 119 pages of typed text. Iconographic material includes 26 figures and 17 tables.
The results obtained were presented in 22 scientific publications.
Keywords: renal and urinary malformation, vesicoureteral reflux, hydronephrosis, early
diagnosis, predisposing factor.
The field of study: pediatria
Aim. Studying the incidence and the argumentation of methods of early diagnosis of renal and
urinary malformations in children in order to develop the medical management algorithm.
1. Studying the incidence of the kidney and urinary tract pathology detected antenatal and
postnatal, according to addressability data.
2. Determining the predisposing factors causing the appearance of congenital malformations
of the kidney and urinary tract.
3. Identifying the role of urinary infection in congenital pathology of the kidney and urinary
tract and developing programs for prevention and treatment during neonatal and infancy
4. Modeling the algorithm for early diagnosis of urinary tract anomalies.
5. Organizing a system to monitor the pathology of the kidney and urinary tract.
Scientific novelty of the results obtained. For the first time in Moldova there have been
conducted scientific researches aimed at determining morbidity caused by anomalies of the
kidney and urinary tract, detected antenatal and postnatal, there have been outlined the ways for
early diagnosis of these diseases and has been developed a monitoring system of this kind of
Scientific problem solved in the research. There has been developed and put into practice at
national level an inedited system to monitor the pathology of the kidney and urinary tract, which
proved to be timely in detecting asymptomatic forms of CM, as well as in defining tactics of
conservative treatment, which, once applied, effectively prevents the appearance of urinary
infection, reduces considerably the number of complications, the need for surgical solutions and
the level of disability in children.
Theoretical significance. The results of scientific studies have a significant practical value,
serving as a basis for timely and qualitative medical assistance for children with congenital
malformations of the kidney and urinary tract.
Applicative value of the work. The study’s results have served as solid guidance in providing a
timely and qualitative medical assistance to children with congenital malformations of the
kidney and urinary tract.
Implementation of scientific results: The results of the study have been implemented in
practice of specialists from the PMSI Mother and Child Institute, contribuiting to the early
diagnosis of congenital malformations of the kidney and urinary tract.