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CNAA / Theses / 2008 / May /

Cerebro-vascular insufficiency in disabled persons afte cranio-cerebrale trauma (neurological and medico-social aspects)

Author: Mihail Ganea
Degree:doctor habilitat of medicine
Speciality: 14.00.13 - Neurology
Scientific consultants: Constantin Eţco
doctor habilitat, professor, Nicolae Testemitanu State University of Medicine and Pharmacy of the Republic of Moldova
Stanislav Groppa
doctor habilitat, professor, Nicolae Testemitanu State University of Medicine and Pharmacy of the Republic of Moldova
Scientific council:


The thesis was presented on the 21 May, 2008
Approved by NCAA on the 19 June, 2008


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235 pages


concequences of craniocerebral trauma, cerebral vascular insufficiency, arterial hipertension, cerebral atterosclerosis, postraumatic neurological syndromes stroke, concomitant pathology early rehabilitation, milimeter waves, epilepsy, cerebral atrophy


In this paper are presented the results of the research concerning the clinical manifestations of long-term effects of craniocerebral trauma and the craniocerebral trauma influence on cerebral circulatory pathology.

Medical-working data of the commission of experts concerning the invalids with craniocerebral trauma consequences and information of own clinical supervision of patients with vascular cerebral pathology that appeared after a long period of craniocerebral trauma are used in this paper. There are described the characteristics of clinical polymorphism and the clinical course of cerebral vascular posttraumatic abnormalities. There was paid attention to the pathogenesis mechanism of posttraumatic cerebral vascular pathology. There is demonstrated the double mechanism of vascular pathology appearance: direct and mediated. The direct mechanism is the vascular wall injuries made by traumatic effects, in result of that there appear vascular scarring, aneurysm, a drying that contribute to cerebral blood reduction, vascular wall rupture, deposition of atherosclerotic plaque. The indirect or mediated mechanism is more complicated and i tis the result of the traumatic effect on hypothalamic region that contributes to the dysfunction of the las tone. In such a case there appear vegetative and homeostatic abnormalities that progressively are transformed into vegetal vascular dystonia, symptomatic hypertension, early cerebral atherosclerosiy, discirculatory encephalopathy, acute abnormalities of cerebral circulation. On the basis of clinical researches on patients with strokes there are elaborated standarts and reports to place this patients in hospital by medical institutions of the Republic.

There were elaborated concrete measures concerning the early and later rehabilitation of patients with stroke and concomitant pathology.

There was elaborated and proposed a new method of rehabilitation treatment – КВЧ therapy using the apparatus UEM – 4, that was constructed by the collaborators of the Institute of Physics of Moldavian Academy of Sciences.

The conclusion of this thesis appreciates the craniocerebral trauma as one of the main risk factor of the cerebral vascular pathology appearance after a long-term period.

As practical recommendations there are presented the standards of hospitalisation of patients with acute cerebral blood flow abnormalities.